The antiviral activity of compounds isolated from Kenyan Carissa edulis (Forssk.)Vahl (Record no. 49107)

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fixed length control field 01673nam a2200337Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625153950.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-14923
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245 10 - TITLE STATEMENT
Title The antiviral activity of compounds isolated from Kenyan Carissa edulis (Forssk.)Vahl
490 0# - SERIES STATEMENT
Volume/sequential designation Journal of Medicinal Plants Research, 4(15), p.1517-1522, 2010
520 3# - SUMMARY, ETC.
Summary, etc. Extracts of a Kenyan medicinal plant, Carissa edulis (Forssk.)Vahl, were subjected to bioactivity guided phytochemical analysis for identification of biological makers of activity. Pure compounds; lupeol, oleuropein, carissol and ß-amyrin were subsequently isolated. In vitroevaluations of the compounds against viral strains of Herpes simples virustypes 1 revealed a significant activity for lupeolat EC 50 of between 2.98 - 4.2 µg/ml for both sensitive and resistant strains with a high therapeutic index (TI > 38). A concentration of the compound at 10.0 µg/ml was virucidal, reducing viral yields in Vero E6 cells by 98.3
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIVIRAL ACTIVITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element LUPEOL
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CARISSA EDULIS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HERPES SIMPLEXVIRUS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tolo, F. M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Rukunga, G. W.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Muli, F. W.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ochora, J. M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Irungu, B. N.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Muthaura, C. N.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wanjiku, C. K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wanjiku, C. K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ngoc, Q.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Hashimoto, K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Asakawa, Y.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1FOkO3sSXWVxDDHoc3PHAfVTrVIaMsRvo/view?usp=drivesdk">https://drive.google.com/file/d/1FOkO3sSXWVxDDHoc3PHAfVTrVIaMsRvo/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-14923 25.06.2025 25.06.2025 Documentos solicitados