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Basics of Polymeric Scaffolds for Tissue Engineering

Tipo de material: TextoTextoSeries ; Journal of ASTM International, 3(9), p.1-10, 2006Trabajos contenidos:
  • Agrawal, C.M
  • Carter, J
  • Ong, J.L
Tema(s): Recursos en línea: Resumen: This review article argues the case that there is a need for careful scaffold science for successful tissue engineering. Polymeric scaffolds should possess certain essential properties. However, these properties are not independent of each other and thus the development of a scaffold requires an optimization process. The article reviews several scaffold fabrication processes to highlight the complexity of the field. Issues related to porosity, permeability, and the need for adequate diffusion characteristics are discussed. Several previous studies on the effects of mixing in bioreactors are reviewed. Lastly, surface modification techniques are presented. In particular, recent work related to glow discharge gas plasma modification of biodegradable polymers is discussed.
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Documentos solicitados Documentos solicitados CICY Documento préstamo interbibliotecario Ref1 B-8673 (Browse shelf(Opens below)) Available

This review article argues the case that there is a need for careful scaffold science for successful tissue engineering. Polymeric scaffolds should possess certain essential properties. However, these properties are not independent of each other and thus the development of a scaffold requires an optimization process. The article reviews several scaffold fabrication processes to highlight the complexity of the field. Issues related to porosity, permeability, and the need for adequate diffusion characteristics are discussed. Several previous studies on the effects of mixing in bioreactors are reviewed. Lastly, surface modification techniques are presented. In particular, recent work related to glow discharge gas plasma modification of biodegradable polymers is discussed.

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