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The effect of pyrrolizidine alkaloids (Senecio vulgaris) on the liver mixed-function oxidase system

Tipo de material: TextoTextoSeries ; Toxicofogy Letters, 5(6), p.369-374, 1980Trabajos contenidos:
  • Eastman, D.F
  • Segall, H.J
Recursos en línea: Resumen: A model system to detect the toxicity of pyrrolizidine alkaloids (PAS)was explored. Using the liver S-10 fraction, the effect of PAS on aniline hydroxylase and aminopyrine N-demethylase was examined. PAS were toxic to the aminopyrine N-demethylase enzyme system while exerting no toxicity on the aniline hydroxylase enzyme system.
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A model system to detect the toxicity of pyrrolizidine alkaloids (PAS)was explored. Using the liver S-10 fraction, the effect of PAS on aniline hydroxylase and aminopyrine N-demethylase was examined. PAS were toxic to the aminopyrine N-demethylase enzyme system while exerting no toxicity on the aniline hydroxylase enzyme system.

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