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Influence of scaffold physical properties and stromal cell coculture on hematopoietic differentiation of mouse embryonic stem cells

Tipo de material: TextoTextoSeries ; BioMaterials, 27, p.6024-6031, 2006Trabajos contenidos:
  • Sabia Taqvi
  • Krishnendu Roy
Tema(s): Recursos en línea: Resumen: Recent studies have suggested that three-dimensional (3D)biomaterial-based scaffolds and dynamic culture conditions could provide significant enhancement in the differentiation efficiency of embryonic stem cells (ESCs). Here we report that scaffold physical properties, like pore size, polymer concentration and compression modulus as well as specific culture conditions, e.g. cell seeding density and coculture with stromal cells can significantly influence hematopoietic differentiation of ESCs. PLLA scaffolds of various polymer concentrations (7.5
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Documentos solicitados Documentos solicitados CICY Documento préstamo interbibliotecario Ref1 B-12379 (Browse shelf(Opens below)) Available

Recent studies have suggested that three-dimensional (3D)biomaterial-based scaffolds and dynamic culture conditions could provide significant enhancement in the differentiation efficiency of embryonic stem cells (ESCs). Here we report that scaffold physical properties, like pore size, polymer concentration and compression modulus as well as specific culture conditions, e.g. cell seeding density and coculture with stromal cells can significantly influence hematopoietic differentiation of ESCs. PLLA scaffolds of various polymer concentrations (7.5

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