Skin tissue engineering-in vivo and in vitro applications.
Tipo de material:
TextoSeries ; Advanced Drug Delivery Reviews, 63(4-5), p.352-366, 2011Trabajos contenidos: - Groeber, F
- Holeiter, M
- Hampel, M
- Hinderer, S
- Schenke-Layland, K
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Significant progress has been made over the years in the development of in vitro-engineered substitutes that mimic human skin, either to be used as grafts for the replacement of lost skin or for the establishment of human-based in vitro skin models. This review summarizes these advances in in vivo and in vitro applications of tissue-engineered skin. We further highlight novel efforts in the design of complex disease-in-a-dish models for studies ranging from disease etiology to drug development and screening.
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